Aus-ROC Endorsed Projects

“Aus-ROC Endorsed Projects” are formally authorized by the Aus-ROC Steering Committee. The process of Endorsement is given in the Aus-ROC Governance Document.

The EXACT Study

The Reduction of oxygen after cardiac arrest (EXACT) is a multi-centre, randomised, controlled trial to determine whether reducing oxygen administration as soon as possible following successful resuscitation from out-of-hospital cardiac arrest (OHCA) compared to current practice of maintaining 100% oxygen improves outcome at hospital discharge.

Funding: 2015 NHMRC Project grant: successfully funded

Contact Investigator: Professor Steve Bernard (

Status: Recruiting

The RINSE Study

The Rapid Infusion of Cold Normal Saline (RINSE) study is a randomised controlled trial, to determine whether paramedic initiated cooling during CPR (using a rapid intravenous infusion of ice-cold normal saline) improves patient survival outcomes compared with usual practice in patients who are being resuscitated from out-of-hospital cardiac arrest.

Funding: NHMRC Project grant: #1010613; 2011-2014; $677,888
Study Progress: Complete. Published in Circulation.
Contact Investigator: Professor Steve Bernard (


Resuscitation and Cardiac Arrest Outcomes: Variation over Regions (RECOVER study)

Despite evidence to suggest significant spatial variation in OHCA incidence, survival and bystander CPR rates, geographic information system and spatial analysis have not been widely used to understand the reasons behind this variation. This is particularly the case in Australia. The aim of this research is to quantify and describe the regional variation of OHCA incidence and survival in Victoria.  The research also aims to identify factors that drive regional differences in OHCA survival and identify modifiable factors associated with survival. This will directly inform strategies aimed at improving outcomes from OHCA across the state, with a particular emphasis on rural areas.

The research results will directly inform ambulance strategies aimed at improving OHCA survival in rural areas.

Study Progress: Complete. See publications.
Contact Investigator: Professor Karen Smith (